Certain factors may trigger your immune system, leading to the disease. Symptoms of systemic lupus erythematosus (SLE) can vary widely from person to person. The normal role of your body’s immune system is to fight off infections and diseases to keep you healthy. Some people may only experience a few mild symptoms, whereas others may be more severely affected. More than 90% of cases occur in females. However, more than 90% of people with systemic lupus erythematosus have skin symptoms. SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) Complications Complications Complications can be severe, leading to organ failure and even death. It's what most people mean when they refer to "lupus". While not the only type of disease known as lupus, systemic lupus erythematosus is the variety that most frequently occurs and is often referred to simply as “lupus.” The disease can be complex and there are many different ways that it can affect the body. The very first sign of lupus is painful joints accompanied by swelling of affected areas like the toes, hands and arms which is very similar to rheumatoid arthritis. Lupus is the short name for the condition called systemic lupus erythematosus (SLE). The times when symptoms are under control are called remissions. Systemic lupus erythematosus is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. Lupus Erythematodes ist eine systemische Autoimmunerkrankung, von der in Deutschland schätzungsweise 400.000 Menschen betroffen sind. Symptoms can be vague and vary between people, and therefore diagnosis can be difficult. Several immunopathogenic pathways play a role in the development of SLE. Even if you usually have mild symptoms, SLE can "flare-up", with symptoms becoming more severe or new symptoms developing. Beim kutanen Lupus, erkennbar an einem schmetterlingsförmigen Ausschlag im Gesicht sowie erhöhter Sonnen-Empfindlichkeit, beschränken sich die Symptome … Fatigue, weakness, joint pain and rash are some of the most common of the symptoms of lupus. Symptoms can vary and may include: skin rashes, joint and muscle pain and fatigue. Seek medical care for lupus if you have rapid swelling of one of your extremities, … SLE can affect both sexes, all ages, and all ethnic groups with widespread geographical and socioeconomic backgrounds. Symptoms include inflammation of different parts of the body including the lungs, heart, liver, joints and kidneys. Frauen erkranken deutlich häufiger an dieser Autoimmunerkrankung als Männer, für Deutschland gilt hier ein Verhältnis von 4:1. The 3 main symptoms of SLE are fatigue, joint pain and … Experts don’t know what causes SLE, but lupus and other autoimmune diseases do run in … It is characterized by the presence of antinuclear antibodies. Your symptoms might develop quickly, or they may come on slowly. In an autoimmune disease like lupus, your immune system starts attacking your own healthy tissues. Systemic lupus erythematosus is a long-term inflammatory condition without a cure. It is considered a disease with unknown cause. Signs and symptoms are related to the affected organs. Systemic lupus erythematosus (SLE) is the most common form of lupus — 70 % of people with lupus have it. Systemic lupus erythematosus (SLE) is a chronic multisystem disorder that most commonly affects women during their reproductive years. Objective: Systemic lupus erythematosus (SLE) presents with psychiatric symptoms in most patients that often remain undiagnosed and untreated. Among young black and Hispanic women ages 15-34, lupus is the 5th and 6th leading cause of death just behind cancer, heart disease and HIV. 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